Unsure of where to best store this information, but it will be helpful for the metabolic engineers:
[ ] For a given biosynthetic route, what are possible drop-in enzyme replacements? Perhaps we know an isozyme, or a homologous enzyme has higher flux in another organism.
[ ] Can candidate biosynthetic routes be prioritized based on ease of cloning, culturing, etc for the chassis? How receptive is the organism to either heterologous expression or overexpression? What is expected translation efficacy and opportunities for codon optimization?
Unsure of where to best store this information, but it will be helpful for the metabolic engineers: