bhclowers
commented
3 years ago Flyback transformers and other switching supplies are exceedingly noisy. I'm not saying they won't work but I have not seen anyone use them successfully. I would imagine that it would be possible to use a switching supply but a considerable amount of voltage conditioning would be needed. Keep in mind that fluctuations in the tube voltage will induce noise on the detector and broaden peaks. Additionally, voltage fluctuations that approach 1% at 10 kV are entirely unacceptable--this will cause the ions to shift constantly and introduces unecessary degress of experimental error (i.e. what is the voltage applied and experienced by the ions?).
I do know that certain vendors have devised specific power supplies that use switching approaches but they are also investing heavily into an engineering team. Provided you don't have the latter, I would recommend the ultravolt series. They are relatively low-cost, compact, and when factoring the amount of time you will spend designing and testing your own solution, this price is worth the money. Just know that you need to pair this with an suitable HV capacitor and hook it to the tube (i.e. the resistor chain) in order to for the circuit to work correctly. It doesn't like working without a load. I don't know the exact underlying architecture but looking at the signal on a scope, they too use a switching supply under the hood--they just smooth it out to a decent degree.
Good luck and wish I had a better answer for you.
AbidHussain70
What kind of power supply will work good for IMS? Power supply source should be DC or can I use circuit made from flyback transformers (relatively cheap option). I noticed that circuit with flyback transformer add noise at higher voltage?