Concentration extrapolation with AUCall goes up when it should go down

billdenney / pknca

An R package is designed to perform all noncompartmental analysis (NCA) calculations for pharmacokinetic (PK) data.

http://billdenney.github.io/pknca/

GNU Affero General Public License v3.0

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Closed billdenney closed 11 months ago

billdenney commented 11 months ago

extrapolate.conc(
   conc = c(1, 0), time = 0:1,
   time.out = 0.75,
   clast = 1,
   auc.type = "AUCall"
)
# [1] 0.75

The value should be 0.25