billzt / PrimerServer2

PrimerServer2: a high-throughput primer design and specificity-checking platform
GNU General Public License v3.0
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Support for degenerate bases #11

Closed billzt closed 2 years ago

billzt commented 2 years ago

Now it simply replaces degenerate bases with a random normal base. However it is not suitable for primers with multiple degenerate bases since it would result in too many mismatches and lose the true amplicon