biobricks-ai / biobricks-okg

An open knowledge graph for BioBricks.ai
MIT License
1 stars 0 forks source link

NICEATM requests consideration of addition of FDALabel. Can we add it to OKG? #11

Open tomlue opened 11 months ago

karafecho commented 8 months ago

Translator pulls in annotation regarding FDA Approval Status using an Annotation Service. I reached out to Andrew Su (Scripps and a Translator / FRINK colleague of mine) about the service, and he replied with the following information:

_The Annotation Service is a side project out of this repo https://github.com/biothings/pending.api (which yes, isn't very well documented). But the FDA approval status really comes from mychem.info, which is a longer-standing and more mature project. You can query mychem via any common chemical identifier (e.g., CHEBI:45783, CHEMBL941, DB00619 -- all for imatinib), and get drug approval status from chembl using the URL syntax below. https://mychem.info/v1/chem/CHEBI:45783?fields=chembl.drug_indications https://mychem.info/v1/chem/CHEMBL941?fields=chembl.drug_indications https://mychem.info/v1/chem/DB00619?fields=chembl.drug_indications_

I'll add that ChEMBL does not distinguish between FDA Approval for Marketing and FDA Clinical Research Phase 4, so FDA approval status is returned as: FDA Clinical Research Phase 1, 2, or 3, or FDA Clinical Research Phase 4 / FDA Approval for Marketing.

Chunlei Wu (cwu@scripps.edu) is the lead developer of mychem. Happy to reach out to him, if that would be helpful.