Score & Fold_change? What do they mean and how to caculate them?

biocore-ntnu / epic

(DEPRECATED) epic: diffuse domain ChIP-Seq caller based on SICER

http://bioepic.readthedocs.io

MIT License

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Score & Fold_change? What do they mean and how to caculate them? #56

Open zhenyisong opened 7 years ago

zhenyisong commented 7 years ago

Epic outputs the calculation result in delim format. The result columns include Score and Fold_change. I am not sure how they are derived from. Do you plan to explain them in details? I check the Sicer website and the software readme, it is not mentioned. It seems a common knowledge I missed.

endrebak commented 7 years ago

The paper explains it. FDR is BH, score is poisson score IIRC. Do not have time to write more now unfortunately but please keep the issue open. I might get around to it someday :)