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biocore-ntnu / epic2

Ultraperformant reimplementation of SICER
https://doi.org/10.1093/bioinformatics/btz232
MIT License
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gap size #48

Open tan5251 opened 3 years ago

tan5251 commented 3 years ago

How can I determine the gap size？ My ChIP-seq data is H3K27me3 modification that is a typical broad peaks. I plan to set the gap size to 5. Is it right? Can you give some suggestions about the selection of gap size? Thanks advance!

endrebak commented 3 years ago

The original manuscript suggested a gap size of 3 for H3K27me3. I have found it to work well :)

tan5251 commented 3 years ago

Thanks for your reply.