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biocore / gneiss

compositional data analysis toolbox
https://biocore.github.io/gneiss/
BSD 3-Clause "New" or "Revised" License
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Balance test #281

Open mortonjt opened 4 years ago

mortonjt commented 4 years ago

One thing that could be useful is a very simple command that allows for a balance test.

It would look something like this

  1. Bootstrap the samples (via multinomial sampling)
  2. Select microbes for numerator / denominator (user specified)
  3. Run statistical test and count up the occurrences to calculate CI and pvalues.

Now that microbes can be directly selected from qurro, this should be easier to implement. CC @fedarko

Relevant issue https://github.com/biocore/qurro/issues/222

mortonjt commented 3 years ago

This is the paper worth citing for this : https://www.biorxiv.org/content/10.1101/134536v2