biod / sambamba

Tools for working with SAM/BAM data
http://thebird.nl/blog/D_Dragon.html
GNU General Public License v2.0
565 stars 105 forks source link

do you support aggregation and dedup in one command? #481

Closed AlisaGU closed 3 years ago

AlisaGU commented 3 years ago

Hi, sambamba is really quick, thanks for your efforts. But, I don't know if it supports aggregation and dedup in one command like this: Merge read groups and mark duplicates per sample (aggregation + dedup).

Can I just pass the multiple inputs belonging to one sample to sambamba in a single command to merge and deduplicate them?

pjotrp commented 3 years ago

Nope.

AlisaGU commented 3 years ago

Thanks for your reply. What should I do to achieve this? use sambamba-merge to merge and sambamba-markdup to dedup?

AlisaGU commented 3 years ago

Hi, Do you agree with my idea?