bioforensics / MicroHapulator

Tools for empirical microhaplotype calling, forensic interpretation, and simulation.
https://microhapulator.readthedocs.io/
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Improve haplotype filtering / genotype calling #114

Closed standage closed 2 years ago

standage commented 2 years ago

Previously, the dynamic filter operated on the average haplotype count at each marker, rather than the total count (for dumb historical reasons). This PR updates the dynamic filter so it operates correctly. The effective coverage parameter was dropped, and support for marker-specific thresholds was added via a CSV file.