I downloaded 5 TCGA-BRCA samples (by choosing specific criteria - I got five tumor samples and their five normal samples) and I run CIRIquant on them. I performed differential expression analysis using CIRI_DE_replicate and I got the final table. My question is: Do you have any idea why would I get good log2 fold change values but not statistically significant (all FDR values are greater than 0.05)?
Hello everyone,
I downloaded 5 TCGA-BRCA samples (by choosing specific criteria - I got five tumor samples and their five normal samples) and I run
CIRIquanton them. I performed differential expression analysis usingCIRI_DE_replicateand I got the final table. My question is: Do you have any idea why would I get good log2 fold change values but not statistically significant (all FDR values are greater than 0.05)?I appreciate your advice and thanks in advance.