bioinform / neusomatic

NeuSomatic: Deep convolutional neural networks for accurate somatic mutation detection
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Any plan to train NeuSomatic models in long-read platforms? #87

Open zhengzhenxian opened 8 months ago

zhengzhenxian commented 8 months ago

Hi, thanks for developing this great tool!

I was able to use the pre-trained models in the GitHub repository designed for short-read data. However, I have no luck in finding any pre-trained models suitable for long-read platforms such as Nanopore or PacBio.

Fortunately, ONT has recently released paired tumor/normal datasets for COLO829/COLO829BL, which can be accessed here. Additionally, PacBio has also made available similar datasets sequenced using their latest Revio systems, which can be found here. Considering the availability of these long-read datasets, I am curious if there are any plans to train models specifically for these two platforms?

Thank you in advance for your assistance!