look at what adds coverage, is good to have as separate operations (namespace, species context?). For example, is there cell-level/organelle-level gene-expression info?
annotating more MetaEdges (not covered by past operations)
click to see MetaEdges
* Chem to Pathway: unclear how helpful this is, since chemicals seem generic (water, ADP, ATP...). [Example](https://api-v3.monarchinitiative.org/v3/api/association?category=biolink:ChemicalToPathwayAssociation&object=Reactome:R-HSA-1369007&direct=true&format=json&limit=500&offset=0). 1 Predicate: `participates_in`
* their prefix `Reactome` differs from what we use (REACT)...so this may require extra post-processing support
(depends on how helpful setting the subject/object namespace is)
* unclear if other Pathway namespaces exist
* Gene to Pathway: previously chose not to annotate because MyGene also covers this info. Also has prefix issue (see Chem to Pathway above). 1 Predicate: `participates_in`
* Gene to GO BiologicalProcess (989349 items): previously chose not to annotate because MyGene also covers this info. Each kind has multiple possible predicates, lots of diff primary knowledge sources
* `actively_involved_in` (797927)
* `acts_upstream_of_or_within` (180729)
* `acts_upstream_of` (9327)
* `acts_upstream_of_or_within_positive_effect` (507)
* `acts_upstream_of_positive_effect` (506)
* `acts_upstream_of_or_within_negative_effect` (178)
* `acts_upstream_of_negative_effect` (175)
* Gene to GO MolecularActivity (848151 items): see notes for BiologicalProcess above
* `enables` (841330)
* `contributes_to` (6821)
* Gene to GO CellularComponent (745837 items): see notes for BiologicalProcess above
* `located_in` (502225)
* `active_in` (145515)
* `part_of` (94049)
* `colocalizes_with` (4048)
* [Gene to Gene ortholog](https://api-v3.monarchinitiative.org/v3/api/association?category=biolink%3AGeneToGeneHomologyAssociation&subject=HGNC%3A9508&direct=false&format=json&limit=10&offset=0): previously chose not to annotate because MyGene also covers this info. 1 predicate (`orthologous_to`, 551383 hits). Seems to be 1 primary knowledge source (panther)
In https://github.com/biothings/biothings_explorer/issues/774, we migrated to the new v3 Monarch API (using the /association endpoint). This is one of the https://github.com/biothings/biothings_explorer/issues/774#issuecomment-1956088818 that may be useful to do.