blab / cartography

Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2
https://doi.org/10.1101/2024.02.07.579374
MIT License
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Drop low- and high-recombination coronavirus-like simulations #31

Closed huddlej closed 1 year ago

huddlej commented 1 year ago

We want to focus our simulations on just the pathogen types we actually analyze, so we don’t need to include all types of recombination.

The primary purpose of simulations is to understand the optimal embedding parameters for a given type of pathogen without overfitting those parameters to real data.

A secondary purpose of simulations is to understand how embeddings represent known populations through time.

We want to use only H3N2-like and moderate-recombination coronavirus-like simulations to tune parameters for H3N2 and SARS-CoV-2.