blab / cartography

Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2
https://doi.org/10.1101/2024.02.07.579374
MIT License
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Implement exhaustive grid search and cross-validation with Snakemake's paramspace interface #4

Closed huddlej closed 3 years ago

huddlej commented 3 years ago

Implements exhaustive grid search and cross-validation using Snakemake's paramspace interface to parallelize embedding and clustering steps for different parameter combinations. We aggregate results into a single table and then process that table with a Jupyter notebook to identify the optimal distance threshold per method and optimal method-specific parameters for t-SNE and UMAP.