search

blab / mers-structure

MERS-CoV spillover at the camel-human interface
Creative Commons Attribution Share Alike 4.0 International
6 stars 3 forks source link

Reviewer 1.4 #27

Closed evogytis closed 6 years ago

evogytis commented 6 years ago

p 10, '...relatively low overall with a mean estimate of N of 3.49 years (95% HPD: 2.71-4.38), and consequently MERS-CoV phylogeny resembles a ladder often seen in human influenza A virus phylogenies...' I would not say that low Ne directly implies a ladder-like tree or vice versa, although it may produce such a tree in combination with highly dispersed sample times.

evogytis commented 6 years ago

Hmm... specify that we mean low Ne relative to sampling time span? As Trevor once pointed out any phylogeny would look like a flu phylogeny when sampled across the right timescale.

trvrb commented 6 years ago

I like the textual revision.