borangao / MESuSiE

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Covariates in fine-mapping #10

Closed Jesson-mark closed 5 days ago

Jesson-mark commented 6 days ago

Hi Boran,

thanks for your tool on trans-ancestry fine-mapping!

Currently I'm trying to do trans-ancestry fine-mapping for two ancestries and both GWASs are performed with some covariates. I noticed that when running fine-mapping using SuSiE the genotype and phenotype are needed to adjusted for covariates.

What I want to confirm is that whether the same step (i.e. adjust for covariates) are required to perform trans-ancestry fine-mapping using MESuSiE.

Thanks!

Jie Wang