bowang-lab / scGPT

https://scgpt.readthedocs.io/en/latest/
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Cell Type Classification Datasets #262

Open nc1m opened 1 month ago

nc1m commented 1 month ago

Hi,

I'm trying to reproduce your cell type classification results on the Multilpe Sclerosis, Myeloid and hPancreas datasets.

In what form are these datasets, since they contain float values I guess they are not raw counts? Have these 3 datasets already been normalized and logarithmized, thus only need to be binned?

nc1m commented 1 month ago

@subercui I'm asking because if you preprocessed the datasets with scanpys normalize_total and log1p, applying numpys expm1 (reverse of log1p) and summing the values for each cell should result in a normalization constant, which is not the case. Thus I'm wondering if I'm missing something.

In #174 it is mentioned that the ms dataset is also normalized in the Tutorial_Annotation.ipynb