search

brentp / slivar

genetic variant expressions, annotation, and filtering for great good.
MIT License
248 stars 23 forks source link

ddc output #113

Open hust-yyan opened 2 years ago

hust-yyan commented 2 years ago

Hi. I've been using your software to perform a pedigree study of whole genome sequencing data.I drew histograms of AB and GQ using Slivar DDC, and next I had a problem selecting thresholds based on these graphs.Could you please tell me how to define the Y-axis count of the graph, and how to select the threshold value suitable for our data? Thank you very much! image

brentp commented 2 years ago

Hi, it's almost always fine to use AB >= 0.2 for hets and this plot shows that as well. Note the orange peak at below 0.2 The y-axis is the number of variants at each allele balance on the x-axis, so it's a histogram.

hust-yyan commented 2 years ago

Thank you very much!