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broadinstitute / CellBender

CellBender is a software package for eliminating technical artifacts from high-throughput single-cell RNA sequencing (scRNA-seq) data.
https://cellbender.rtfd.io
BSD 3-Clause "New" or "Revised" License
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Negative raw counts #334

Closed IrinaVKuznetsova closed 4 months ago

IrinaVKuznetsova commented 4 months ago

Dear CellBender team,

I've got filtered count matrix with negative count values for some genes. I wonder if what would cause such behaviour ? Raw counts matrix should have only positive counts Thanks