This adds a module, adapt.utils.predict_activity, that reads and calls a trained model of guide-target activity. It also includes changes to construct_guide() to use this module so that the only guides output are those predicted to be highly active against their intended targets (according to a threshold defined in adapt.utils.predict_activity). Using this is optional and can be set with the --predict-activity-model-path argument to design.py.
This adds a module,
adapt.utils.predict_activity, that reads and calls a trained model of guide-target activity. It also includes changes toconstruct_guide()to use this module so that the only guides output are those predicted to be highly active against their intended targets (according to a threshold defined inadapt.utils.predict_activity). Using this is optional and can be set with the--predict-activity-model-pathargument todesign.py.