This PR makes a small modification to the coverage_analysis module, adding a class that allows the determination of guide-target binding (equivalently, whether a guide covers a target sequence) to be made according to a predictive model -- the guide is said to bind/cover/detect a target if the predicted activity is highly activity (i.e., exceeds a threshold). This PR also adds arguments to analyze_coverage.py to use this feature.
This PR makes a small modification to the
coverage_analysismodule, adding a class that allows the determination of guide-target binding (equivalently, whether a guide covers a target sequence) to be made according to a predictive model -- the guide is said to bind/cover/detect a target if the predicted activity is highly activity (i.e., exceeds a threshold). This PR also adds arguments toanalyze_coverage.pyto use this feature.