broadinstitute / adapt

A package for designing activity-informed nucleic acid diagnostics for viruses.
MIT License
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Add option to write mean activity of guides in coverage analysis #43

Closed haydenm closed 3 years ago

haydenm commented 3 years ago

This adds an argument to analyze_coverage.py, --write-mean-activity-of-guides, which writes to a file the mean activity of a guide set across the targets. The PR also adds the functionality in coverage_analysis.py to compute these values.

Note that the mean activity excludes primers -- i.e., it only considers guides and does not account for whether the primers in a design would amplify the target sequence. This is accounted for, however, by the output of --write-frac-bound.