Incorporate basic substitution model activity decay

broadinstitute / adapt

A package for designing activity-informed nucleic acid diagnostics for viruses.

MIT License

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Incorporate basic substitution model activity decay #47

Closed priyappillai closed 3 years ago

priyappillai commented 3 years ago

Incorporate the likelihood of decaying activity over time via the model in adapt-seq-design/proactive_design (written by David K. Yang) into ADAPT's output. Make optional due to added runtime.

haydenm commented 3 years ago

I should add, since you specifically asked me to look at how the mutator is placed, I think everything is pieced together well and sensibly. It does make things a little messy with the binary predictor and sequence context (I think you had brought this up too at one point), but it's not a problem.