broadinstitute / adapt

A package for designing activity-informed nucleic acid diagnostics for viruses.
MIT License
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Add option to design naively using n most common sequences #54

Closed priyappillai closed 2 years ago

priyappillai commented 2 years ago

Allow design_naively to output the n most common sequences as a guide set. Make as a variant of mode output, using --mode-n input to specify how many sequences to output. Also, fix bug in design_naively that raised an error if a reference sequence was not input even if none was needed. Note: For window sizes >1 guide length, the best guide set will be determined by the efficiency of MODE_N guides at each site with no penalty for a larger guide set