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broadinstitute / cell-health

Predicting Cell Health with Morphological Profiles
MIT License
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Investigate specific CRISPR genes #53

Closed gwaybio closed 3 years ago

gwaybio commented 4 years ago

Similar to #52 - Do any of the genes we CRISPR targeted produce known cell health phenotypes? Do we predict these with our models?

gwaybio commented 4 years ago

Dependent on #35

gwaybio commented 4 years ago

This note came up again at meeting 12/16

There was specific rationale for selecting these genes. Some genes were known to trigger certain phenotypes captured via cell health assays. We should determine what information we have about the genes. If I can't find anything, then I will ask Paquita.

AnneCarpenter commented 4 years ago

Paquita mentioned they have some annotations of the genes, documenting their expected behavior. I'm not sure how structured it is, but it may help identify positive controls.

gwaybio commented 3 years ago

addressed in #141