broadinstitute / genetic-prevalence-estimator

https://genie.broadinstitute.org/
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Make it more obvious the preliminary estimates are not manually reviewed #261

Closed sambaxter closed 1 month ago

sambaxter commented 1 month ago

Anne and Heidi suggested making it more obvious that the automated/preliminary estimates are not manually reviewed. To accomplish this we can make a few changes.

1) Rename the column to "Preliminary genetic prevalence estimates (ClinVar LP/P and gnomAD HC LoF)"

2) Add a hover over saying "Preliminary genetic prevalence estimates are algorithmically generated using ClinVar pathogenic/likely pathogenic variants and gnomAD high confidence predicted loss-of-function variants only. These estimates have not been manually reviewed and may contain non-disease causing variants. Use with caution."

image

3) On the estimate page update the note at the top to say "This list was algorithmically generated for the gene [GENE], with the transcript {TRANSCRIPT]. This algorithm uses ClinVar pathogenic/likely pathogenic variants and gnomAD high confidence predicted loss-of-function variants only. These estimates have not been manually reviewed and may contain non-disease causing variants. Use with caution."