Closed nawatts closed 3 years ago
Carrier frequency is calculated as 2pq, where p is the frequency of the reference allele and q the allele frequency of the alternate allele.
2pq
p
q
In rare disease research, because q is often very small, p is often simplified to 1, simplifying carrier frequency to 2q.
2q
Carrier frequency is calculated as
2pq, wherepis the frequency of the reference allele andqthe allele frequency of the alternate allele.In rare disease research, because q is often very small,
pis often simplified to 1, simplifying carrier frequency to2q.