broadinstitute / gistic2

Genomic Identification of Significant Targets in Cancer (GISTIC), version 2
MIT License
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Unreliable GISTIC2 results #20

Open tanbiswas opened 1 year ago

tanbiswas commented 1 year ago

Hi

Initially I ran gistic2 on hiplot platform using 31 samples as an input. Where I got some amplified and deleted peaks. Later, I added one more samples to the segment file and put 32 samples segmented file as an input. It generated all the result files. However, we got a peak that was initially showing deleted, now GISTIC2 is calling the same peak is as amplified.

Can you please explain this?