Open liskinsk opened 2 months ago
The reference sequence for ALDOA at https://gnomad.broadinstitute.org/gene/ENSG00000149925?dataset=gnomad_r4 is incorrect It does NOT match https://www.uniprot.org/uniprotkb/P04075/entry
This is not simply due to polymorphisms at a few positions. Spot checking across the whole sequence finds it to all be incorrect. I suspect there is a translation problem.
If so, the substitutions are also likely to not be correctly translated.
What you did:
The reference sequence for ALDOA at https://gnomad.broadinstitute.org/gene/ENSG00000149925?dataset=gnomad_r4 is incorrect It does NOT match https://www.uniprot.org/uniprotkb/P04075/entry
This is not simply due to polymorphisms at a few positions. Spot checking across the whole sequence finds it to all be incorrect. I suspect there is a translation problem.
If so, the substitutions are also likely to not be correctly translated.
What happened: