Closed shntnu closed 3 years ago
@gwaygenomics
In https://github.com/broadinstitute/grit-benchmark/blob/main/1.calculate-metrics/cell-health/0.calculate-grit.ipynb, it says
Some perturbations have only one guide per gene, these cannot have grit scores
But aren't you computing grit at the replicate level? And you have 6 replicates for most guides so this should be possible.
If you're computing grit at the perturbation level, are you first aggregating the replicates somewhere?
(Meta: Consider adding Discussions to this repo, and move this there?)
@gwaygenomics
In https://github.com/broadinstitute/grit-benchmark/blob/main/1.calculate-metrics/cell-health/0.calculate-grit.ipynb, it says
But aren't you computing grit at the replicate level? And you have 6 replicates for most guides so this should be possible.
If you're computing grit at the perturbation level, are you first aggregating the replicates somewhere?
(Meta: Consider adding Discussions to this repo, and move this there?)