Scope of application of ichorCNA?

broadinstitute / ichorCNA

Estimating tumor fraction in cell-free DNA from ultra-low-pass whole genome sequencing.

GNU General Public License v3.0

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Scope of application of ichorCNA? #125

Open h170607 opened 11 months ago

h170607 commented 11 months ago

hi, Can ichorCNA be used to estimate the purity and ploidy of tumor tissue samples? Can it be used to analyze wgs, wes, and panel sequencing data? If yes, how to adjust the parameters according to the sample type or data type? Thanks!

best,

jgarces02 commented 5 months ago

According to this issue (#20), it seems you can use ichorCNA for WES data if you have a matched normal.