broadinstitute / ichorCNA

Estimating tumor fraction in cell-free DNA from ultra-low-pass whole genome sequencing.
GNU General Public License v3.0
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Running ichorCNA on cell free mitochondrial DNA #131

Open Ons14 opened 4 months ago

Ons14 commented 4 months ago

Hello,

I'm a master's student working on cell-free mitochondrial DNA. I found this article "The landscape of cell‑free mitochondrial DNA in liquid biopsy for cancer detection" (https://pubmed.ncbi.nlm.nih.gov/37828498/) where they used ichorCNA (commit 5bfc03e) but they didn't specify the modifications made to ensure the pipeline works on chrM.

Any tips or suggestions would be greatly appreciated.

Thank you very much.