Can ichorCNA for tumor samples

broadinstitute / ichorCNA

Estimating tumor fraction in cell-free DNA from ultra-low-pass whole genome sequencing.

GNU General Public License v3.0

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Can ichorCNA for tumor samples #79

Open jfrigola opened 3 years ago

jfrigola commented 3 years ago

Hello ichorCNA team! I'd like to know if your softwar can also be used to analyze shallow whole genome sequencing data comming from tumor tissue samples (not cfDNA but solid samples of the actual tumor). If so, is the tumor fraction prediction still accurate and meaningful (I guess it should be understood as the purity of the tumor sample)?

Thanks in advance!

gavinha commented 3 years ago

Hi @jfrigola

Yes, you can use ichorCNA for tumor samples as well.

Best, Gavin