broadinstitute / ichorCNA

Estimating tumor fraction in cell-free DNA from ultra-low-pass whole genome sequencing.
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What are the columns in the cna.seg file? #92

Open LN908 opened 3 years ago

LN908 commented 3 years ago

Can anyone explain what each column is in the cna.seg output?

I understand the following: chr - chromosome number start - start of chromosome bin end - end of bin

But what exactly are these values? copy.number - is this the uncorrected copy number of that bin? event - ? logR - what is this the logR of? I see many negative numbers and positive ones that end up being called NEUT? How is this calculated? Is this number used to determine the logR_Copy_Number? subclone.status - is this if there is a subclone present or not? 1 = present, 0=not present? Corrected_Copy_Number Corrected_Call logR_Copy_Number

Thank you in advance!