broadinstitute / infercnv

Inferring CNV from Single-Cell RNA-Seq
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residual expression scale in plot #593

Open mea2712 opened 1 year ago

mea2712 commented 1 year ago

Hello I'm trying to understand the residual expression scale in infercnv.png ("Modified Expression"): The plots seem to have a scale ~ 0.6 to 1.4, but when I look at exp <- read.table("expr.infercnv.dat") range(expr) I get [1] 0.6650464 3.4663837 1) Is the expression normalized such that 1 means no over/under expression, that is, a state 3 in the i6 HMM? 2) Are the upper/ lower bounds to this scale, such that a state 6 has always the same maximum expression? Or is this dependent upon the data? Thanks!