broadinstitute / lincs-cell-painting

Processed Cell Painting Data for the LINCS Drug Repurposing Project
BSD 3-Clause "New" or "Revised" License
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Add consensus perturbation signatures #36

Closed gwaybio closed 4 years ago

gwaybio commented 4 years ago

My current plan is as follows:

Unifying documentation for this step from https://github.com/broadinstitute/lincs-cell-painting/issues/4#issuecomment-620839509 and https://github.com/broadinstitute/lincs-cell-painting/pull/34#issuecomment-629307961

shntnu commented 4 years ago
  • [ ] 5. Output a separate file for a feature selected consensus signature (derived after calculating consensus)

You would not be able to do replicate_correlation selection on consensus profiles. You'd need to do this on the Level 4b data across all plates instead. But also note that when we do so, we first sample a subset of the plates to avoid inflating the report replicate correlations.

I'd skip 5. for now unless it is blocking

gwaybio commented 4 years ago

closed in #40