broadinstitute / lincs-profiling-complementarity

Analyzing and comparing signal found in different profiling technologies
BSD 3-Clause "New" or "Revised" License
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[Response to Review] Add target and pathway labels for prediction #59

Closed gwaybio closed 2 years ago

gwaybio commented 2 years ago

A reviewer asked why MOA predictions were poor and thought that making predictions with pathways instead might improve signal.

The first step in performing this analysis is to generate new y matrices. In this PR, I map compounds to targets and targets to Gene Ontology terms. I also form new y matrices with these labels.

This is part 1 of 2 PRs to perform the target and pathway prediction analysis