broadinstitute / lincs-profiling-complementarity

Analyzing and comparing signal found in different profiling technologies
BSD 3-Clause "New" or "Revised" License
5 stars 5 forks source link

[Response to Review] Comparing cell count, reproducibility, and cell death predictions #63

Closed gwaybio closed 2 years ago

gwaybio commented 2 years ago

The reviewers were concerned that we did not factor in the possibility of high cell death rates.

We can mostly explain this as a time point decision (which is important to elucidate in the manuscript), but I also add a figure that demonstrates high cell death is only a factor for a small minority of compounds, particularly at high dose.

cell_count_reproducibility