broadinstitute / lincs-profiling-complementarity

Analyzing and comparing signal found in different profiling technologies
BSD 3-Clause "New" or "Revised" License
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[Response to Review] Adding MOA matching column to figure 2 with same compounds #69

Closed gwaybio closed 2 years ago

gwaybio commented 2 years ago

The previous updated figure 2 (see #62 and #68) added percent matching of MOAs across all doses. That analysis used any MOA that had more than 3 compounds. Because we were considering all doses, this increased the set of MOAs that passed the filtering criteria.

Category Number of MOAs
Within dose 127
Across dose 210

In this PR, I add a new column that computes across dose MOA percent matching for only the 127 MOAs that we used in the previous analyses. We call this column All*

I also update the related supplementary figure to:

Updated Fig 2

figure2

Updated Related Sup Fig

moa_target_label_hits