This PR is the start of moving this repo to support GRCh38.
Major changes:
Updated process_context_ht and removed process_vep to reflect updated inputs for GRCh38 and updated utility functions in gnomad_methods repo (rmc/utils/generic.py)
Minor changes:
Removed all references to v2 flagship LoF resources (no longer needed; rmc/resources/gnomad.py)
Bumped GENCODE and VEP versions; also converted TableResources to VersionedTableResources (with TODOs; rmc/resources/reference_data.py)
Updated default reference and gnomAD versions (rmc/resources/resource_utils.py)
Updated freezes and removed references to obsolete ExAC resources (rmc/resources/rmc.py)
This PR is the start of moving this repo to support GRCh38.
Major changes:
process_context_ht
and removedprocess_vep
to reflect updated inputs for GRCh38 and updated utility functions in gnomad_methods repo (rmc/utils/generic.py
)Minor changes:
rmc/resources/gnomad.py
)rmc/resources/reference_data.py
)rmc/resources/resource_utils.py
)rmc/resources/rmc.py
)rmc/utils/generic.py
)rmc/utils/generic.py
)process_context_ht
call inrmc/utils/missense_badness.py