search

broadinstitute / seqr

web-based analysis tool for rare disease genomics
GNU Affero General Public License v3.0
176 stars 89 forks source link

ACMG Calculator state update bug #2573

Closed drtconway closed 2 years ago

drtconway commented 2 years ago

To reproduce:

  1. go to an unclassified variant
  2. Open the ACMG Calculation dialogue.
  3. You should see Score = 0, Classification = Unknown, Criteria Applied = No criteria applied.
  4. Toggle BS1_P from N to Y.
  5. You should see Score = -1, Classification = Likely Benign, Criteria Applied = BS1_P.
  6. Now toggle BS1_P back to N.
  7. You should see the same as step 3 above, but instead you see Score = -1, Classification = Likely Benign, Criteria Applied = No criteria applied.

I am observing this behaviour on the MCRI instance, but I don't believe there are any downstream (MCRI specific) changes that could be remotely relevant.

Appearance at step 3.

Appearance at step 5.

Appearance at step 7.

hanars commented 2 years ago

I have verified that this is also a bug in our seqr instance. Thanks for letting us know!

hanars commented 2 years ago

this is fixed in the latest seqr release