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broadinstitute / seqr

web-based analysis tool for rare disease genomics
GNU Affero General Public License v3.0
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Variant filtering by CADD #361

Closed anneodonnell closed 3 years ago

anneodonnell commented 6 years ago

Could you add CADD to the deleterious prediction filtering options. One issue is that I could filter missense and synonymous variants at different CADD scores given synonymous variants never have CADD scores as high as missense variants.

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anneodonnell commented 5 years ago

In a recent call with Illumina, Daniel asked if we could also sort by Primate AI scores. So we'd like to sort by CADD, REVEL, PrimateAI and SpliceAI on new search.

hanars commented 5 years ago

This ticket is originally about filtering, not sorting. In new search you can already sort by cadd, revel and splice AI. Can you clarify which fields you would like to add for sorting, and which you would like for filtering?

anneodonnell commented 5 years ago

oh, sorry, I was trying to not duplicate tickets. I'm going to open a new one with the sorting information.

hanars commented 3 years ago

Filtering by all available in silico predictors has been added