Update in silico score information & display

[lynnpais]

Is your feature request related to a problem? Please describe. Need revisions to the work done in #3505

Describe the solution you'd like

1. Spelling/ spacing All CAPS for - FATHMM, SIFT, CADD, REVEL, MPC, VEST Requires partial caps and spaces removed for - PolyPhen, MutTaster, MutPred, PrimateAI

2. Remove citation in the hover over for SpliceAI and MPC as they were not changed/ not included in the new guidelines published

3. Reorder the scores as follows CADD, REVEL, VEST, Mutpred2, MPC, SpliceAI. Others can go in the show more section.

Describe alternatives you've considered NA

Additional context NA

[jklugherz]

@lynnpais

2 says to remove citations for two in silico predictors. should I replace the citation with an older guideline or just remove the citation?

[hanars]

remove the citation, I don't think we know exactly where those cutoffs came from but I don't think they were published I think they were internal decision

[jklugherz]

are Mutpred and Mutpred2 the same score? should I use one or the other?

[hanars]

They are different versions of the same score. The actual versioning of the data is handled in the seqr loading pipeline and search backend, from the front end perspective the API response should have mutpred as the name of the field in the response, and we should show it to the user without the version number

[jklugherz]

out of the possible predictors, which ones do require a citation in the hover over?

[hanars]

out of the possible predictors, which ones do require a citation in the hover over?

cadd fathmm gerp mpc mut_pred polyphen primate_ai revel sift vest

[hanars]

these have been updated