search

broadinstitute / ssGSEA2.0

Single sample Gene Set Enrichment analysis (ssGSEA) and PTM Enrichment Analysis (PTM-SEA)
Other
230 stars 79 forks source link

More input genes, better results? #27

Closed LynnChan99 closed 9 months ago

LynnChan99 commented 10 months ago

Hi, I am using ssgsea in my recent project recently. However, I am little confused about this probelm: If we input more genes, will we get better infiltration result?

Looking forward to your reply, and thanks a lot!

drmani commented 10 months ago

ssGSEA is designed to be used with all the genes provided as input, ranked based on appropriate criteria. So, the more genes you provide as input, the more robust the results will be -- more genes will increase the overlap with genesets.

LynnChan99 commented 10 months ago

OK, I see.Thank you for your reply!

---- Replied Message ---- | From | @.> | | Date | 11/09/2023 01:10 | | To | @.> | | Cc | LynnChan99 @.>, Author @.> | | Subject | Re: [broadinstitute/ssGSEA2.0] More input genes, better results? (Issue #27) |

ssGSEA is designed to be used with all the genes provided as input, ranked based on appropriate criteria. So, the more genes you provide as input, the more robust the results will be -- more genes will increase the overlap with genesets.

— Reply to this email directly, view it on GitHub, or unsubscribe. You are receiving this because you authored the thread.Message ID: @.***>