bulik / ldsc

LD Score Regression (LDSC)
GNU General Public License v3.0
601 stars 331 forks source link

How to test the null hypothesis of rg=1 #390

Open Apprentice2 opened 11 months ago

Apprentice2 commented 11 months ago

Thank you for developing this wonderful tool, LDSC. I would like to evaluate the genetic correlation of two traits using LDSC. I would like to prove that the two traits are not completely genetically correlated. I know that LDSC usually tests rg=0 as the null hypothesis, but is there any way to test rg=1 as the null hypothesis? I would be grateful if you could enlighten me.