correlation value higher than 1

bulik / ldsc

LD Score Regression (LDSC)

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Open yildizkoca opened 6 months ago

yildizkoca commented 6 months ago

I'm getting the following values for my GWAS correlation analysis, why is correlation bigger than 1?

Genetic Correlation: 1.0316 (1.1478) Z-score: 0.8988 P: 0.3688

aksarkar commented 3 weeks ago

@yildizkoca The estimate is not constrained to be within the bounds [-1, 1] in order that it remain unbiased.

The estimate and standard error are consistent with the genetic correlation = 0.