bulik / ldsc

LD Score Regression (LDSC)
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INTERCEPT FLAG #431

Open zara03 opened 6 months ago

zara03 commented 6 months ago

Hi, I want to ask one more thing when should I use intercept flag ? Like i have 2 GWAS summary statistics from European ancestry, when i compute regression with intercept flag its p value is significant but when i dont use intercept flag its non significant? Can you please explain when to use this flag?

aksarkar commented 6 months ago

@zara03 You should not use those flags.