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bvieth / powsimR

Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses.
https://bvieth.github.io/powsimR/
Artistic License 2.0
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FDR #54

Closed gcrynen closed 3 years ago

gcrynen commented 3 years ago

I am having an issue with marginal FDR , they are very high, I ran several of the files and I keep getting 95% FDR (nominal 10%) and sensible TPRs. I ran the examples several times, restarted R and ran it but results dont change, FDR is very high unlike the example results. thank you.

bvieth commented 3 years ago

Hi,

I am sorry to hear that you encounter this issue. I had a look into it and reverted to an older version, tagged now as 1.2.4a .

Best Beate