Closed jjgao closed 1 year ago
This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.
This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.
Cohort Stats: 570 pats - profiled using whole-genome and transcriptome sequencing
Data Availability: Clinical data - Supp Table 1, 2 Mutation rates - Source Data Extended Data Fig. 2 Mutational Signatures - Source Data Extended Data Fig. 5 Germline variants - Source Data Extended Data Fig. 8
Genomic data available at: https://www.bcgsc.ca/downloads/POG570/ POG570_small_mutations.txt.gz - Complete list of somatic small mutations (SNVs and indels). POG570_TPM_expression.txt.gz: Expression by gene in TPM Table_S1_Demographics.xlsx - Cohort demographics Table_S2_Treatment.xlsx - Treatment and survival data Table_S7_Sequencing.xlsx - Sequencing parameters
Clinical and genomic data (MAF, CNA and Expression) split to multiple studies by cancer type is also available here: https://www.personalizedoncogenomics.org/cbioportal/. This studies can be downloaded & combined.
Status: Study can be curated from the supplemental data but I have also emailed the author (May 26, 2021) if they can share the combined dataset since it is already been transformed to portal formats in their local instance.
This issue has been automatically marked as stale because it has not had recent activity. It will be closed if no further activity occurs. Thank you for your contributions.
The study is released at https://www.cbioportal.org/study/summary?id=pog570_bcgsc_2020.
https://www.nature.com/articles/s43018-020-0050-6
This study contains the following data types:
To-do: